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Live 3-D imaging highlights cellular activity during embryonic heart development

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Live imaging techniques have given Spanish researchers deeper insight into the development of the embryonic heart in mice. Their analysis reveals the coordination that occurs between cardiac progenitor cells – cells similar to stem cells that can change into another specific type of cell during heart development. They found that progenitor cells go through alternate phases of changing into cardiac muscle (differentiation) to initiate early heart function, and contribute to cardiac morphogenesis. The study, which was originally published as a preprint in bioRxiv, appears today in the journal eLife.

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